
South America Tours & Vacations
Steeped in ancient traditions and adventurous landscapes, South America offers charismatic cities and breathtaking natural wonders. From the Amazon rainforest to Patagonian glaciers, white-sand beaches to Andean plains, the wonders of wildlife unlike anywhere else in the world abound. Whether interested in cultural treasures or timeless landscapes, South America is exceptionally diverse and endlessly enchanting. Zicasso travel specialists have planned over 40,000 trips to this region of the world and look forward to designing yours.
Top South America Destinations
Discover extraordinary places and those rarely explored–these are a few to inspire your travels.
Explore Our Trip Ideas
Let these itineraries inspire your personalized travel experience

8 Day Trip IdeaFrom $4,300
Paradisiacal Peru: Lima, Cusco, Sacred Valley Tour

9 Day Trip IdeaFrom $5,200
Colombia Cultural Immersion: 9-Day Tour of Bogota, Medellin, and Cartagena

10 Day Trip IdeaFrom $9,800
10-Day Brazil: Wildlife and Nature Explorer

12 Day Trip IdeaFrom $14,500
Argentina Explorer: Capital, Forests, Andes Mountains, and Wine Country

14 Day Trip IdeaFrom $11,600
Heart of Patagonia: Two-Week Tour of Chile and Argentina

14 Day Trip IdeaFrom $17,100
14 Day Galapagos Adventure
How Zicasso Works
Here's how we create life-enriching, luxury travel experiences
1.Share Your Travel Dreams
Zicasso specializes in custom tours, vacations, and safaris tailored to your interests and preferences. From private African safaris to culinary experiences in Europe, submit a trip request to share your ideas and travel style.
2.Meet Your Travel Specialists
To ensure a personalized experience, we'll carefully handpick and introduce you to two of our top travel specialists, each with unsurpassed destination knowledge and local insight aligned to your luxury travel dreams.
3.Design Your Perfect Journey
Compare the expertise of two specialists with itineraries crafted exclusively for you. You can refine these further and choose your preferred proposal. Our unique process ensures a more creative, personalized, and expertly crafted trip.

12 Day Trip IdeaFrom $12,700
Cultural Kaleidoscope Road Trip from Salta to the Atacama

13 Day Trip IdeaFrom $6,900
Highlights of Chile and Easter Island Tour: Expansive Desert to Remote Island

21 Day Trip IdeaFrom $23,600
Riveting Luxuries of Chile and Argentina Tour: Surreal Landscapes to Buzzing Cities

9 Day Trip IdeaFrom $3,700
Wonders of Chile: City, Desert, Mountain Tour

15 Day Trip IdeaFrom $8,000
Marvels of Peru and Brazil Tour: Natural and Cultural Discoveries

12 Day Trip IdeaFrom $6,800
Coffee, Chocolate & Cocktails Tour of Costa Rica
Popular Destinations in South America
Travel Tips for Your South America Trip
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Reviews of Zicasso's South America Tours & Vacations
Based on 2301 verified traveler reviews.
My trip was an incredible adventure, which I feel fortunate to have experienced. The excursions were well chosen and hotels outstanding. The logistics of a long trip with over six destinations and activities in the desert, mountains, and urban areas were artfully arranged by Zicasso’s travel specialist and supported by vendors and transit agencies. I had a support network that allowed me to totally enjoy the beautiful and diverse environments, cultures, and activities.
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We take great pleasure in saying our Patagonian adventure through Zicasso and the tour operator was near perfect. Our sincere thanks to our travel specialist and everyone at the tour operator for the red-carpet treatment we received at every destination on our itinerary: namely Buenos Aires, Iguazú, Bariloche, El Calafate, and El Chalten. We commend everyone involved in the personalized communication, planning and execution of our two exciting weeks traveling throughout Argentina.
Beginning in December 2025, the travel specialist and his team worked out every detail of travel in Argentina's fall season: all our domestic flights, customized tours, airport transfers, and, most importantly, the most knowledgeable, engaging guides we could ever have imagined. We can't make enough positive comments about our first Patagonian adventure.
Every driver arrived promptly, putting us immediately at ease. Every evening, team members messaged us on WhatsApp to remind us of the next day's transfers and tours. They followed up immediately with answers to any questions we had.
All of our guides were exceptional. Their passion and depth of knowledge made our tours more fascinating and entertaining than any we've ever experienced. We could not have planned anything remotely close to the guides the tour operator included for each tour.
We will most assuredly utilize the services of the travel specialist at the best tour company we have ever found for adventures in South America.
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We had great hotels, great guides, great experiences, and great support via WhatsApp from Zicasso's travel specialists during the trip.
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We had a great travel experience with Zicasso's travel company. Brazil is a wonderful country to visit. The people we encountered were very courteous, helpful, and happy.
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It was a very well-organized trip with a lot of attention to detail. The tour guides were professional and kind. I fell sick the first day in Santiago and the hotel staff were extremely helpful with organizing a doctor and helping me get appropriate medication in the middle of the night. Patagonia is a truly wonderful place and the arrangements were excellent. Thank you.
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Zicasso’s travel specialist was very easy to work with and put together the unique itinerary that we were looking for. He was also very attentive to our needs during the trip. I would definitely recommend him and his company to anyone traveling to southern South America.
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