Masterpieces of Italy Tour: From David to The Last Supper

What to expect on this itinerary
Italy is like a treasure chest brimming with art, architecture, and innovation. Experience artistic brilliance with insightful guides accompanying you on an Italy tour personalized to your favorite inspirational masterpieces. Medieval villages overtake hillsides. Ancient arenas continue to permeate the skyline. Frescoes and mosaics retain their bright colors and continue to tell stories through the ages. From Rome to Milan, Florence to Venice, the masters of Italy crafted detailed works that have withstood the tests of time, filling every moment of your luxury Italian tour with a wealth of excellence, wonder, charm, and prestige.
Customizable Itinerary
Rome – Arrive the Eternal City with a Fascinating Walking Tour and Dinner
Rome represents the brilliance of the classical era and the importance of artistry to daily life beyond the emperors and senators of the empire. Delicate and dramatic frescoes decorate churches. The Spanish Steps shimmer with opulent marble and elegant design. The dome of the Pantheon has inspired architects and artists for two millennia, including the legendary Michelangelo and Brunelleschi. Your flight lands at Rome Fiumicino Airport. Your private transfer greets you upon your arrival and escorts you to a gorgeous hotel in the historical city center. Locals and visitors wander along the designer shops along Via del Corso.
The scent of strawberries drifts out of a gelaterie, emanating from the fruity gelato. You take a moment to settle into the comforts of your luxury hotel set inside a former magnificent palace. Your guide greets you in the lobby, eager to introduce you to the masterful works of Rome on a walking tour through the city center. Consider learning more about the top Italy travel agents who will help design, create, and guide your dream Italy vacation. You can see the golden façade of Castel Sant’Angelo across the bridge over the Tiber River. The structure began as a mausoleum for Emperor Hadrian and was converted into a papal fortress centuries later. The 10 angelic statues line the cobblestone bridge, each designed with a careful eye to detail by master sculptor Bernini. His work guides your exploration of the city center, as you make your way to Piazza Navona to view the elaborate Fountain of the Four Rivers, which Bernini also designed.
What's Included:
Rome – Enjoy the Rich History of Rome on a Private Guided Full Day Tour
Rome – Visit Vatican City and the Remarkable Churches Decorating Rome
Florence – Wander Historic of Assisi and Enjoy a Fabulous Tour of Florence
Florence – Explore the Uffizi, Pitti Palace, and Hidden Artisan Workshops
Florence – Discover the Accademia, San Marco Church, and Central Market
Venice – Relish the Churches and Cuisine of Bologna and Art of Padua
Venice – Absorb the Art and Architecture on a Full Day Tour of Venice
Milan – Venture to Milan to View the Duomo and Santa Maria delle Grazie
Milan – Depart for Home
Trip Highlights
- Discover the brilliance of Italian masters up-close and in person under the instruction of expert guides in art history, culture, and style
- Visit the Vatican Museum to stand beneath the iconic images draping over the walls and ceiling as painted by Michelangelo in the 16th century
- Trace the evolution of sculpture in Florence to enjoy the masterful works carved out of marble, including standing beneath Michelangelo’s David
- Revel in the feeling of grandeur and amazement as you stand in front of Leonardo da Vinci’s masterpiece The Last Supper in Santa Maria delle Grazie
- Witness the beginnings of the Renaissance while visiting the Scrovegni Chapel in Padua, where Giotto first applied human characteristics upon divine figures
- Wander the galleries of Villa Borghese, home to one of the greatest private collections of art
- Traverse the fabulous halls of the Accademia in Venice in search of the fabled Venetian masters inside the galleries in which they studied
- Relish the unique ambiance of great Italian cities whose architecture is as masterful as the artwork which they contain
Detailed Description
The masters of Italian art have shaped history through the way they captured allegories, biblical tales, and daily life. Your personalized Italy tour immerses you in the artworks of the past on a 10-day tour highlighting masterpieces, from the Colosseum to the Trevi Fountain, David to the frescoes in the Scrovegni Chapel. The thrilling exploration begins with your arrival in Rome. Your private transfer greets you at Fiumicino Airport and escorts you to a gorgeous hotel within the historical city center. Discover the iconic fountains and piazzas of the city with a private guide and explore the ancient architecture and preserved walkways winding between the Forum and Palatine Hill. Witness the elaborate collection of works inside the Vatican Museum, including works of Raphael and Michelangelo. Stroll through the elaborate galleries of the Borghese Villa to view one of the world’s most elaborate private art collections.
Visit the town of Assisi, in Umbria to follow in the footsteps of St. Francis. The basilica remains a dramatic piece of architecture home to fascinating frescoes and the antique tomb of the eponymous saint. Once in Florence, the images of the Renaissance spring to life. Enjoy a walking tour of the city’s endless wealth of structures designed by master architects, from the Medici chapel at San Lorenzo to the idyllic dome of the cathedral at the heart of the historic center crafted by Brunelleschi. Visit the masterpieces housed in the Uffizi and Pitti Palace before meeting with contemporary artisans preserving the traditions of quality goods handcrafted in Florence. Explore the Central Market for an enriching, flavorful experience and follow the historic evolution of sculpting in Florence, reaching the pinnacle with Michelangelo’s David.
Bologna is a city regarded for its cuisine but retains elements of masterful artwork and architecture on display around the city center. Stop in the quiet city of Padua en route to Venice to see Giotto’s masterworks decorating the Scrovegni Chapel, which various artists attribute bringing in the birth of the Renaissance. Venice is a city of grandeur embodied in the gorgeous palazzos and charming neighborhoods. Enjoy the graceful ambiance with tours of the Accademia Gallery and churches embedded with historical artwork, including St. Mark’s Basilica. You reach the marvels of Milan for a guided tour to take in the magnificent cathedral and The Last Supper by da Vinci. Your private transfer escorts you to Malpensa Airport on the final day of your Italy tour with plenty of time to check into your flight home.
Consider browsing our other Italian tours to gain further inspiration in perfecting your own dream Italy vacation of a lifetime.
Starting Price
$4,500 per person (excluding international flights)
Your Zicasso trip is fully customizable, and this sample itinerary is a starting place for your travel plans. Actual costs are dynamic, and your selection of accommodations and activities, your season of travel, and other such variables will bring this budget guideline up or down. Throughout your planning experience with your Zicasso specialist, your itinerary is designed around your budget. You can book your trip when you are satisfied with every detail. Planning your trip with a Zicasso travel specialist is a free service.
What's Included
- Accommodations
- In-country transportation
- Some or all activities and tours
- Expert trip planning
- 24x7 support during your trip
Your final trip cost will vary based on your selected accommodations, activities, meals, and other trip elements that you opt to include.
Verified Traveler Reviews
Based on 732 reviews
The trip was awesome. The accommodations were very nice. We just did not realize how much walking we would do, but we managed. There were a few hiccups, but nothing major.
Our transport from the airport to the hotel in Venice went smoothly. We definitely appreciated the private transfer after seeing the crowd on the public transportation. My sister was a little disappointed that the gondolier did not sing to us in Italian, but she thought the ride was very relaxing. The tour guide for St. Mark's was very knowledgeable and informative. Venice was a lovely and unique city. We were surprised by the narrow walkways/streets and canals; but came to appreciate them. It gave Venice its charm. The transport from the hotel to the train station was right on time and the guy at the train station was great. He explained exactly what we needed to do to catch the train to our next destinations. We really appreciated his help.
The transport from the train station to the car rental agency was okay. The driver spoke little English and the A/C did not work in the vehicle. The driver did try everything to work the A/C and did apologize that it was not working. The driver dropped us off at the wrong spot at the rental car place. He dropped us off where you turn in the cars. We had to walk to where you rent the cars with our luggage. The car-rental line was extremely long and somewhat confusing. There were no instructions to take a number. We only knew because a nice couple informed us to do so. And there were so many other car-rental places with no lines.
We explored Cinque Terre, Pisa, and Florence during our time in Impruneta. We really enjoyed the cooking class and winery tour you scheduled for us; our guide was a great teacher. Driving in Florence was a little confusing with the ZTLs, but I think we did okay. Little did we know how much we would appreciate the ZTLs while walking around in Florence. We walked and shopped in Florence. We even did a tour at the Accademia Gallery to see the statue of David.
Returning the vehicle was way easier than renting it and our next transport picked us up right where we were dropped off. We felt very comfortable navigating the train station for our train ride to Rome, thanks to the train station lesson we received from the guy in Venice. The train rides went very smoothly. The transport from the station in Rome to our hotel went very well. He literally dropped us off right in front of the hotel.
Rome was different. It had the narrow, quaint streets between buildings which made Rome very walkable. However, we did not expect cars/motorcycles to be driving down these narrow streets as well. It made for interesting walks. We really enjoyed our tours with our guide. She was very knowledgeable and informative. She also allowed us to go at our own pace. Needless to say, our pace became slower than usual from all the walking we already did in Venice and Florence. Our feet were starting to hurt, even though we wore comfortable shoes the whole time. We also enjoyed the Vatican Necropolis. I was extremely humbled that I was able to kneel and pray before the actual remains of St. Peter. I am very grateful we were allowed to get into that tour. Although Rome was different, it was very historical and a lot to take in. There was just so much history everywhere you turned. Rome was really inspiring.
Our transport from the hotel back to the airport was on time and went very well. The driver spoke very good English and gave us some additional interesting facts while on our way to the airport. We were ready to go home, but also sad to be leaving.
Thank you for putting the details of the trip together. The trip would not have been as great as it was without you.
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My trip was fantastic! Every single minute of it! I was in Europe city-hopping for 16 days and every aspect of the trip was perfect! My travel specialist and her team, who planned my trip and gave me support throughout it, couldn't have done a better job - it truly was the trip of a lifetime!
We started out planning it about a year ago. I contacted Zicasso about planning a multi-city trip and I listed the places that I wanted to visit. I am a woman traveling solo, so I asked for guides for many places that I wanted to visit - people who knew the cities and the best way to get around, great places to eat, etc. The guides were awesome - I had four of them and they each had a background in history or art history, so they were perfect companions to visit museums and palaces with.
I also had a somewhat unusual request - I wanted to go to thrift shops in three cities. I strongly believe in recycling and finding a new home for pre-loved items. I did end up going to thrift stores and some shops featuring local designers and artisans, and found some absolute treasures to take home with me! And I spent one wonderful morning at a Paris flea market with my Parisian guide, and we had a grand time! I found some jewelry and a small piece of art to take home with me. She had me try my first crepe (I've never had one before) and also something that I'm going to misspell that, when pronounced, sounds like "shoe" - yummy!
I wanted to see a show at the Moulin Rouge, but did not want to go to a club at night by myself, so my guide escorted me and we had a wonderful time! Similarly, I wanted to go to a jazz club one evening and my guide escorted me there, where we had a blast! She accompanied me to the Louvre and made sure I got to see all the pieces I was interested in seeing. She also took very good pictures of me at all the spots we visited so I could send them back home. I'll give her a 5+ star rating as a guide! She was just lovely!
My next stop was Prague and my guide was just as superb! She introduced me to espresso tonics (I'm sipping one right now as I've been making them at home - I love them!) and she gave me a wonderful guided tour of the city. The next day we did some thrifting and visited stores featuring local designers. Again, I found some treasures. Another 5+ star guide!
From there I took the train to Vienna, where my guide brought me on an amazing walking tour of the city. She was so knowledgeable about the city and its history - you could tell it is her passion. She also brought me to thrift stores and local artisan shops and again I found even more treasures! We visited museums and enjoyed lunch and coffees together. And she escorted me to a blues club one evening where we had a blast listening to live classic American blues (my real love, along with jazz). My guide is just so delightful! Highly recommended if you are interested in visiting Vienna.
From there I flew to Venice - my final destination. My guide was so knowledgeable about the artwork that we saw at the Peggy Guggenheim Collection - it felt as if by seeing the paintings we were visiting old friends of his! And he also took me to see Doge's Palace and on a gondola ride.
On day two in Venice, we went by boat to Murano, where we visited the glass factory and saw the glassblowers working. I had done very well at sticking to my budget for the trip until I got to the Murano factory showroom. I love glass and the pieces they were selling were all sublime! So much work went into them. I ended up buying two pieces that are being shipped to me so I did not have to worry about transporting them on the plane. And our tour guide at the factory even gifted me a necklace that I'm wild about after serving me prosecco in a handblown glass.
From there, we headed to the island of Burano and had lunch. I've got wonderful pictures of the colorful houses there. As I said, the trip could not have been better. The hotels were all fabulous in each city - centrally located and an easy walk to restaurants and shops. The beds were super-comfortable and each room was very quiet - I slept like a log from all the walking that I did every day.
I even managed to send postcards to friends and family from each city - not an easy task since not many people use snail mail anymore! But my guides were all determined to help me find postage and they did - every one of them!
Each hotel offered breakfast and the food was delicious. I'm on a keto diet but came off of it for this trip so I could enjoy the local specialties. The breakfasts were all buffet-style and offered everything you could imagine - eggs, bacon, sausage, all kinds of breads and rolls, pastries, fresh fruit and juice, yogurt, and the best coffee! Every hotel had an excellent buffet. They were all 4-star hotels and each room was charming. The staff at each hotel were also very accommodating, wanting to ensure that I had everything I needed.
There is nothing that the travel specialist and her team left out. Her team even arranged for a last-minute guide to help me get from my hotel to the airport in Venice and make sure I was at the right ticket counter (I was a little concerned about finding the water taxi and then finding the right place to go at the airport). He wheeled and carried my luggage, which by this time was heavy!
The whole trip was perfect and I'm hoping to return in a couple of years. I'd like to make a trip to the Christmas markets in Europe - especially Prague and Vienna - and you know which guides I'm going to be requesting! The whole experience was top-notch! Have no concerns at all about working with this company - they're the best! I thank each and every one who was involved in my trip. It really was perfect!
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Our first trip to Italy was a romantic anniversary celebration, and thanks to Zicasso’s travel specialist and our travel company, it became one of the most extraordinary and meaningful travel experiences of our lives. It was everything we had dreamed of, and so much more!
From our very first conversations, she took the time to understand who we are as travelers: our love of art, architecture, history, culture, food, wine, and lifelong learning. She translated those passions into an imaginative, beautifully personalized journey through Rome, Tuscany, Florence, and Venice.
One of her greatest gifts is her intuitive understanding of the rhythm of travel. We wanted days filled with discovery, learning, and new experiences, but also leisurely afternoons and evenings to wander cobblestone streets, linger over wonderful meals, and simply absorb the atmosphere of Italian life. She struck that balance perfectly. Our itinerary was wonderfully rich, yet never rushed or overscheduled.
The private guides she selected were exceptional: not simply knowledgeable, but gifted teachers and storytellers who brought centuries of Italian history, art, architecture, and culture vividly to life. In Florence, for example, our guide helped us explore the Renaissance through fascinating stories of the Medici family, Michelangelo’s creative process, and the philosophy of Humanism. Our visits to the great museums and historic landmarks became intellectually stimulating and deeply engaging experiences.
She also introduced us to Italy’s living traditions: a fabulous food tour in Rome, wine tasting in Tuscany, explorations of enchanting medieval towns and villages, and boat excursions to Murano and Burano, where we discovered the centuries-old artistry of glassblowing and lacemaking. These experiences gave us a wonderful sense of the richness and continuity of Italian culture.
Her choices of accommodations were equally inspired. Each was distinctive, beautifully located, and full of character, from a charming, peaceful boutique hotel near the Pantheon in Rome, to a magical stay in a medieval Tuscan village, an elegant Art Deco hotel in Florence, and a fairytale suite in Venice. Every setting added another layer of romance and delight to our anniversary celebration. And the cuisine was heavenly! Every meal was memorable, culminating in a dreamy farewell dinner beside a Venetian canal.
Behind all this magic was the travel specialist’s impeccable planning, extraordinary attention to detail, and genuinely proactive care. Every transition, from airports and private transfers to trains and boats, was seamlessly coordinated.
One small example perfectly captures her approach. When our train from Florence to Venice was delayed, we contacted the travel specialist to let her know. She immediately reassured us that she was already monitoring our train and had informed our guide in Venice of the delay. There was nothing for us to do but relax, enjoy the ride, and look forward to the magnificence of Venice! That kind of thoughtful anticipation gave us complete peace of mind throughout our travels.
Equally special was her warmth and genuine personal connection. She was always accessible, and we found ourselves exchanging messages most days, not because anything needed fixing, but simply because it was such a pleasure sharing our experiences with her. She combines exceptional professionalism, creativity, and meticulous organization with kindness, generosity of spirit, and a contagious passion for sharing the beauty of her country. By the end of our journey, we felt we had gained not only an extraordinary travel advisor, but also a wonderful new friend.
Italy opened our minds, elevated our souls, and deeply touched our hearts. Our travel specialist didn’t simply organize a magnificent vacation; she opened the door to a country and culture we have now fallen completely in love with.
We cannot recommend our travel specialist and travel company highly enough. For anyone seeking a thoughtfully curated, culturally immersive, deeply personal, and truly unforgettable Italian journey, she is an exceptional choice.
We are already dreaming of returning to explore Sicily and Sardinia with our family, and there is absolutely no question who we will call!
Thank you for giving us far more than a beautiful vacation. You gave us an extraordinary gift: memories, discoveries, and connections we will treasure for the rest of our lives.
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We could not be more pleased with the itinerary Zicasso’s travel specialist organized on our behalf. We were visiting Rome with our daughter, son-in-law, and 11-year-old twin granddaughters. From our pick-up at the airport to our final drop-off heading home, everything ran like clockwork.
The tours of the Colosseum and the Vatican, our cooking class, and fresco art painting experience were all well-suited to every member of the family. The guides and hostesses were all lovely, very knowledgeable, and made every experience memorable, especially for our grandchildren. We would not hesitate to recommend the travel specialist to anyone looking for a truly authentic Roman adventure.
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We very much enjoyed our recent 15-day trip to Italy. Accommodations were comfortable and clean, and in good locations with a nice breakfast provided. All drivers were professional, polite, and on time.
The tour guides provided to the Colosseum/Forum, Vatican Museum, Borghese Gallery, Uffizi Gallery, and Accademia Gallery were all excellent and knowledgeable. We also appreciate the recommendations for restaurants near the hotel in Rome. All were excellent.
We felt that overall there was a good balance of planned activities and free time.
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Our 16-day trip through Venice, Florence, Tuscany, Sorrento and the Amalfi Coast, and Rome was outstanding in every detail. Every transfer ran on time, every guide was knowledgeable and warm, and every hotel was a great choice.
Our favorites were the private lagoon boat trip in Venice, the Brunello wine and cheese tour, the pasta class at a Tuscan farm, Pompeii, the Capri cruise, and the Vatican tour. We couldn’t have asked for better planning or support. We highly recommend Zicasso's travel company.
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