Masterpieces of Italy Tour: From David to The Last Supper

View of Piazza Venezia in Rome, Italy

What to expect on this itinerary

Italy is like a treasure chest brimming with art, architecture, and innovation. Experience artistic brilliance with insightful guides accompanying you on an Italy tour personalized to your favorite inspirational masterpieces. Medieval villages overtake hillsides. Ancient arenas continue to permeate the skyline. Frescoes and mosaics retain their bright colors and continue to tell stories through the ages. From Rome to Milan, Florence to Venice, the masters of Italy crafted detailed works that have withstood the tests of time, filling every moment of your luxury Italian tour with a wealth of excellence, wonder, charm, and prestige.

Countries Visited

Italy, Vatican City

Places Visited

Rome, Vatican City, Florence, Assisi, Padua, Venice, Milan

Suggested Duration

10 Days

Customizable Itinerary

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Day 1

Rome – Arrive the Eternal City with a Fascinating Walking Tour and Dinner

Rome represents the brilliance of the classical era and the importance of artistry to daily life beyond the emperors and senators of the empire. Delicate and dramatic frescoes decorate churches. The Spanish Steps shimmer with opulent marble and elegant design. The dome of the Pantheon has inspired architects and artists for two millennia, including the legendary Michelangelo and Brunelleschi. Your flight lands at Rome Fiumicino Airport. Your private transfer greets you upon your arrival and escorts you to a gorgeous hotel in the historical city center. Locals and visitors wander along the designer shops along Via del Corso.

The scent of strawberries drifts out of a gelaterie, emanating from the fruity gelato. You take a moment to settle into the comforts of your luxury hotel set inside a former magnificent palace. Your guide greets you in the lobby, eager to introduce you to the masterful works of Rome on a walking tour through the city center. Consider learning more about the top Italy travel agents who will help design, create, and guide your dream Italy vacation. You can see the golden façade of Castel Sant’Angelo across the bridge over the Tiber River. The structure began as a mausoleum for Emperor Hadrian and was converted into a papal fortress centuries later. The 10 angelic statues line the cobblestone bridge, each designed with a careful eye to detail by master sculptor Bernini. His work guides your exploration of the city center, as you make your way to Piazza Navona to view the elaborate Fountain of the Four Rivers, which Bernini also designed.

What's Included:

Transfer
Accommodation
Tour
Day 2

Rome – Enjoy the Rich History of Rome on a Private Guided Full Day Tour

Day 3

Rome – Visit Vatican City and the Remarkable Churches Decorating Rome

Day 4

Florence – Wander Historic of Assisi and Enjoy a Fabulous Tour of Florence

Day 5

Florence – Explore the Uffizi, Pitti Palace, and Hidden Artisan Workshops

Day 6

Florence – Discover the Accademia, San Marco Church, and Central Market

Day 7

Venice – Relish the Churches and Cuisine of Bologna and Art of Padua

Day 8

Venice – Absorb the Art and Architecture on a Full Day Tour of Venice

Day 9

Milan – Venture to Milan to View the Duomo and Santa Maria delle Grazie

Day 10

Milan – Depart for Home

Trip Highlights

  • Discover the brilliance of Italian masters up-close and in person under the instruction of expert guides in art history, culture, and style
  • Visit the Vatican Museum to stand beneath the iconic images draping over the walls and ceiling as painted by Michelangelo in the 16th century
  • Trace the evolution of sculpture in Florence to enjoy the masterful works carved out of marble, including standing beneath Michelangelo’s David
  • Revel in the feeling of grandeur and amazement as you stand in front of Leonardo da Vinci’s masterpiece The Last Supper in Santa Maria delle Grazie
  • Witness the beginnings of the Renaissance while visiting the Scrovegni Chapel in Padua, where Giotto first applied human characteristics upon divine figures
  • Wander the galleries of Villa Borghese, home to one of the greatest private collections of art
  • Traverse the fabulous halls of the Accademia in Venice in search of the fabled Venetian masters inside the galleries in which they studied
  • Relish the unique ambiance of great Italian cities whose architecture is as masterful as the artwork which they contain 

Detailed Description

The masters of Italian art have shaped history through the way they captured allegories, biblical tales, and daily life. Your personalized Italy tour immerses you in the artworks of the past on a 10-day tour highlighting masterpieces, from the Colosseum to the Trevi Fountain, David to the frescoes in the Scrovegni Chapel. The thrilling exploration begins with your arrival in Rome. Your private transfer greets you at Fiumicino Airport and escorts you to a gorgeous hotel within the historical city center. Discover the iconic fountains and piazzas of the city with a private guide and explore the ancient architecture and preserved walkways winding between the Forum and Palatine Hill. Witness the elaborate collection of works inside the Vatican Museum, including works of Raphael and Michelangelo. Stroll through the elaborate galleries of the Borghese Villa to view one of the world’s most elaborate private art collections.

Visit the town of Assisi, in Umbria to follow in the footsteps of St. Francis. The basilica remains a dramatic piece of architecture home to fascinating frescoes and the antique tomb of the eponymous saint. Once in Florence, the images of the Renaissance spring to life. Enjoy a walking tour of the city’s endless wealth of structures designed by master architects, from the Medici chapel at San Lorenzo to the idyllic dome of the cathedral at the heart of the historic center crafted by Brunelleschi. Visit the masterpieces housed in the Uffizi and Pitti Palace before meeting with contemporary artisans preserving the traditions of quality goods handcrafted in Florence. Explore the Central Market for an enriching, flavorful experience and follow the historic evolution of sculpting in Florence, reaching the pinnacle with Michelangelo’s David.

Bologna is a city regarded for its cuisine but retains elements of masterful artwork and architecture on display around the city center. Stop in the quiet city of Padua en route to Venice to see Giotto’s masterworks decorating the Scrovegni Chapel, which various artists attribute bringing in the birth of the Renaissance. Venice is a city of grandeur embodied in the gorgeous palazzos and charming neighborhoods. Enjoy the graceful ambiance with tours of the Accademia Gallery and churches embedded with historical artwork, including St. Mark’s Basilica. You reach the marvels of Milan for a guided tour to take in the magnificent cathedral and The Last Supper by da Vinci. Your private transfer escorts you to Malpensa Airport on the final day of your Italy tour with plenty of time to check into your flight home.

Consider browsing our other Italian tours to gain further inspiration in perfecting your own dream Italy vacation of a lifetime. 

Starting Price

$4,500 per person (excluding international flights)

Your Zicasso trip is fully customizable, and this sample itinerary is a starting place for your travel plans. Actual costs are dynamic, and your selection of accommodations and activities, your season of travel, and other such variables will bring this budget guideline up or down. Throughout your planning experience with your Zicasso specialist, your itinerary is designed around your budget. You can book your trip when you are satisfied with every detail. Planning your trip with a Zicasso travel specialist is a free service.

What's Included

  • Accommodations
  • In-country transportation
  • Some or all activities and tours
  • Expert trip planning
  • 24x7 support during your trip

Your final trip cost will vary based on your selected accommodations, activities, meals, and other trip elements that you opt to include.

4.9

Verified Traveler Reviews

Based on 624 reviews

Italy Travel Review: Venice, Cinque Terre, Pisa, Florence, Impruneta, Rome, St. Mark's Basilica, Vatican, Cooking Class, Winery Tour, Art, 9-Day Trip

The trip was awesome. The accommodations were very nice. We just did not realize how much walking we would do, but we managed. There were a few hiccups, but nothing major.

Our transport from the airport to the hotel in Venice went smoothly. We definitely appreciated the private transfer after seeing the crowd on the public transportation. My sister was a little disappointed that the gondolier did not sing to us in Italian, but she thought the ride was very relaxing. The tour guide for St. Mark's was very knowledgeable and informative. Venice was a lovely and unique city. We were surprised by the narrow walkways/streets and canals; but came to appreciate them. It gave Venice its charm. The transport from the hotel to the train station was right on time and the guy at the train station was great. He explained exactly what we needed to do to catch the train to our next destinations. We really appreciated his help.

The transport from the train station to the car rental agency was okay. The driver spoke little English and the A/C did not work in the vehicle. The driver did try everything to work the A/C and did apologize that it was not working. The driver dropped us off at the wrong spot at the rental car place. He dropped us off where you turn in the cars.  We had to walk to where you rent the cars with our luggage. The car-rental line was extremely long and somewhat confusing. There were no instructions to take a number. We only knew because a nice couple informed us to do so. And there were so many other car-rental places with no lines. 

We explored Cinque Terre, Pisa, and Florence during our time in Impruneta. We really enjoyed the cooking class and winery tour you scheduled for us; our guide was a great teacher. Driving in Florence was a little confusing with the ZTLs, but I think we did okay. Little did we know how much we would appreciate the ZTLs while walking around in Florence. We walked and shopped in Florence. We even did a tour at the Accademia Gallery to see the statue of David. 

Returning the vehicle was way easier than renting it and our next transport picked us up right where we were dropped off. We felt very comfortable navigating the train station for our train ride to Rome, thanks to the train station lesson we received from the guy in Venice. The train rides went very smoothly. The transport from the station in Rome to our hotel went very well. He literally dropped us off right in front of the hotel.

Rome was different. It had the narrow, quaint streets between buildings which made Rome very walkable. However, we did not expect cars/motorcycles to be driving down these narrow streets as well. It made for interesting walks. We really enjoyed our tours with our guide. She was very knowledgeable and informative. She also allowed us to go at our own pace. Needless to say, our pace became slower than usual from all the walking we already did in Venice and Florence. Our feet were starting to hurt, even though we wore comfortable shoes the whole time. We also enjoyed the Vatican Necropolis. I was extremely humbled that I was able to kneel and pray before the actual remains of St. Peter. I am very grateful we were allowed to get into that tour. Although Rome was different, it was very historical and a lot to take in. There was just so much history everywhere you turned. Rome was really inspiring.

Our transport from the hotel back to the airport was on time and went very well. The driver spoke very good English and gave us some additional interesting facts while on our way to the airport. We were ready to go home, but also sad to be leaving.  

Thank you for putting the details of the trip together. The trip would not have been as great as it was without you.

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France, Czech Republic, Austria, Italy Tour Review: Paris, Prague, Vienna, Venice, Murano, Burano, Museums, Palaces, Flea Market, Moulin Rouge, Jazz Club, Gondola Ride, Glass Factory, 16-Day Trip

My trip was fantastic! Every single minute of it! I was in Europe city-hopping for 16 days and every aspect of the trip was perfect! My travel specialist and her team, who planned my trip and gave me support throughout it, couldn't have done a better job - it truly was the trip of a lifetime!

We started out planning it about a year ago. I contacted Zicasso about planning a multi-city trip and I listed the places that I wanted to visit. I am a woman traveling solo, so I asked for guides for many places that I wanted to visit - people who knew the cities and the best way to get around, great places to eat, etc. The guides were awesome - I had four of them and they each had a background in history or art history, so they were perfect companions to visit museums and palaces with.

I also had a somewhat unusual request - I wanted to go to thrift shops in three cities. I strongly believe in recycling and finding a new home for pre-loved items. I did end up going to thrift stores and some shops featuring local designers and artisans, and found some absolute treasures to take home with me! And I spent one wonderful morning at a Paris flea market with my Parisian guide, and we had a grand time! I found some jewelry and a small piece of art to take home with me. She had me try my first crepe (I've never had one before) and also something that I'm going to misspell that, when pronounced, sounds like "shoe" - yummy!

I wanted to see a show at the Moulin Rouge, but did not want to go to a club at night by myself, so my guide escorted me and we had a wonderful time! Similarly, I wanted to go to a jazz club one evening and my guide escorted me there, where we had a blast! She accompanied me to the Louvre and made sure I got to see all the pieces I was interested in seeing. She also took very good pictures of me at all the spots we visited so I could send them back home. I'll give her a 5+ star rating as a guide! She was just lovely!

My next stop was Prague and my guide was just as superb! She introduced me to espresso tonics (I'm sipping one right now as I've been making them at home - I love them!) and she gave me a wonderful guided tour of the city. The next day we did some thrifting and visited stores featuring local designers. Again, I found some treasures. Another 5+ star guide!

From there I took the train to Vienna, where my guide brought me on an amazing walking tour of the city. She was so knowledgeable about the city and its history - you could tell it is her passion. She also brought me to thrift stores and local artisan shops and again I found even more treasures! We visited museums and enjoyed lunch and coffees together. And she escorted me to a blues club one evening where we had a blast listening to live classic American blues (my real love, along with jazz). My guide is just so delightful! Highly recommended if you are interested in visiting Vienna.

From there I flew to Venice - my final destination. My guide was so knowledgeable about the artwork that we saw at the Peggy Guggenheim Collection - it felt as if by seeing the paintings we were visiting old friends of his! And he also took me to see Doge's Palace and on a gondola ride.

On day two in Venice, we went by boat to Murano, where we visited the glass factory and saw the glassblowers working. I had done very well at sticking to my budget for the trip until I got to the Murano factory showroom. I love glass and the pieces they were selling were all sublime! So much work went into them. I ended up buying two pieces that are being shipped to me so I did not have to worry about transporting them on the plane. And our tour guide at the factory even gifted me a necklace that I'm wild about after serving me prosecco in a handblown glass.

From there, we headed to the island of Burano and had lunch. I've got wonderful pictures of the colorful houses there. As I said, the trip could not have been better. The hotels were all fabulous in each city - centrally located and an easy walk to restaurants and shops. The beds were super-comfortable and each room was very quiet - I slept like a log from all the walking that I did every day.

I even managed to send postcards to friends and family from each city - not an easy task since not many people use snail mail anymore! But my guides were all determined to help me find postage and they did - every one of them!

Each hotel offered breakfast and the food was delicious. I'm on a keto diet but came off of it for this trip so I could enjoy the local specialties. The breakfasts were all buffet-style and offered everything you could imagine - eggs, bacon, sausage, all kinds of breads and rolls, pastries, fresh fruit and juice, yogurt, and the best coffee! Every hotel had an excellent buffet. They were all 4-star hotels and each room was charming. The staff at each hotel were also very accommodating, wanting to ensure that I had everything I needed.

There is nothing that the travel specialist and her team left out. Her team even arranged for a last-minute guide to help me get from my hotel to the airport in Venice and make sure I was at the right ticket counter (I was a little concerned about finding the water taxi and then finding the right place to go at the airport). He wheeled and carried my luggage, which by this time was heavy!

The whole trip was perfect and I'm hoping to return in a couple of years. I'd like to make a trip to the Christmas markets in Europe - especially Prague and Vienna - and you know which guides I'm going to be requesting! The whole experience was top-notch! Have no concerns at all about working with this company - they're the best! I thank each and every one who was involved in my trip. It really was perfect!

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Italy Trip Review: Rome, Colosseum, Vatican, Cooking Class, Fresco Painting Experience, 1 Week

We could not be more pleased with the itinerary Zicasso’s travel specialist organized on our behalf. We were visiting Rome with our daughter, son-in-law, and 11-year-old twin granddaughters. From our pick-up at the airport to our final drop-off heading home, everything ran like clockwork.

The tours of the Colosseum and the Vatican, our cooking class, and fresco art painting experience were all well-suited to every member of the family. The guides and hostesses were all lovely, very knowledgeable, and made every experience memorable, especially for our grandchildren. We would not hesitate to recommend the travel specialist to anyone looking for a truly authentic Roman adventure.

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Italy Vacation Review: Le Marne, Art Tour, Museums, 9 Days

It was well organized and met my needs completely. The guides and drivers (except for the one to the airport on 6/23) were great. I was particularly surprised and pleased by the art tour on 6/22.

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Italy Trip Review: Rome, Florence, Vatican, Sistine Chapel, Colosseum, 2 Weeks

Zicasso set us up with a wonderful travel agent. The process of choosing and communicating through the Zicasso system was easy and helpful.

The travel specialist and her team planned a wonderful 15-day trip, with nine days in Rome and four days in Florence. She found us great accommodations that included a kitchen, which was a must for us. Other travel agents were not able to provide such accommodations.

The drivers we had were professional and picked us up on time. The guides were experts in their field and generally had taught at universities. The guides were very personable and tailored the tours to our interests.

She arranged all the necessary skip-the-line tours. We went to the Vatican with three different tours: the Sistine Chapel, the Gardens, and the necropolis to see St. Peter's tomb.

There were a couple of hiccups in this perfectly planned itinerary. Each time, the travel specialist and her staff were immediately available and guided us through solutions, such as trying to get to the Colosseum during the Roman Marathon.

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Italy Tour Review: Venice, Florence, San Gimignano, Siena, Rome, Vatican, Amalfi Coast, Capri, Sorrento, Positano, Doge's Palace, Colosseum, Palatine Hill, Boat Ride, 12 Days

This was possibly the best trip of my life!

Once I arrived in Venice and put myself in the hands of Zicasso’s tour company, I was supremely well taken care of.

I left my passport on the plane, so I was held up in the airport for probably two hours. This was the first time I used the emergency number (or the chat app). The communication was answered immediately and we were able to let my first guide know I was being held up. I thought the first person who helped me was just someone to get me to the hotel, but she was also a guide in the sense that she described many of the things we saw on the way to the hotel. A very pleasant and gracious guide who made sure also that I was prepared for where to be the next day. It was a very great first experience of the tour company’s service.

Throughout this adventure, the guides were outstanding, the hotels were located practically on top of the interesting sites (especially in Rome) and very pleasant to be in.

Also, I continued to use the emergency number or the chat app multiple times. They were very responsive, very pleasant, and perfectly helpful each time. I don't know if I was high-maintenance compared to other clients the tour company has had, but though I felt like it in my mind, I was treated completely graciously each time.

I loved every destination and I loved having a structured tour, combined with a good portion of free time to explore on my own. Perfect.

I was very well guided on each travel day, being met by drivers to drop me off and to pick me up, and the train travel was very fun.

I think there was only one guide who I thought was just going through the motions, but all the other guides were the height of professionalism. I loved being met by our guides at Doge's Palace, which was absolutely outstanding. Walking around old Florence was great fun! The drive out to San Gimignano and Siena was well-planned and well-guided! In Rome, the guide who took us to the Colosseum and Palatine Hill was outstanding, and it was a great outing. (I had also already pretty much visited all the sights since my hotel was practically in the middle of it all.)

The trip to the Vatican was a whole other story. Unfortunately, I forget that guide's name. This guide was also excellent—entertaining, informative, approachable, and professional. The trip to the Amalfi Coast was a long train ride, followed by a very long car ride, but it was worth it. What a beautiful setting! My trip to Capri was absolutely fulfilling and I was a little sad to say goodbye to the guide—we connected with him so well. The next day was our boat tour from Sorrento to Amalfi and Positano. I absolutely enjoyed being guided by our guides! On the way back after that beautiful excursion, we were just cruising along the water, 1970s music playing, wind rushing by and I had a peak moment of happiness. Truly.

This trip was as if the tour company had read my mind and provided even more than I had imagined. I come away deeply grateful.

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Customizable Itinerary

This is a sample itinerary to inspire a personalized trip designed with your travel specialist.

34,000+ Verified Traveler Reviews