Wonders of South America: Chile, Argentina, Uruguay and Brazil Tour

Puerto Varas with Sacred Heart church and Osorno Volcano in Chile

What to expect on this itinerary

Urbane sophistication and the grandness of nature, the epicurean pleasures of a fine glass of wine and the cultural delights of a tango show, the Great Outdoors and the Marvels of Civilization; all of this and more can be found in stupendous South America. From the Andres to the Atlantic, from the Plaza de Armas to the Plaza de Mayo, this is a journey that will stir your imagination and leave you begging for more.

Countries Visited

Argentina, Brazil, Chile, Uruguay

Places Visited

Santiago, Puerto Varas, Bariloche, Buenos Aires, Colonia del Sacramento, Montevideo, Iguazú Falls

Suggested Duration

18 Days

Customizable Itinerary

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Day 1

Santiago – Arrival in South America

Touch down on the outskirts of scintillating Santiago, nestled between the calm blue waters of the Pacific, the teeth-like protrusions of the Andes, and filled with culture and history unlike any other Latin American capital. A private driver will be awaiting your arrival and will transport you to your elegant and perfectly located hotel, where you can rest and recover from your long journey before spending the afternoon exploring.

Your expertly guided tour of Santiago begins at the gorgeous Moneda Palace, a neoclassical marvel that is one of the only buildings of its kind on the continent. Turn next to the Plaza de Armas, the heart and soul of Santiago, surrounded by the venerable and august Metropolitan Cathedral, the stately Central Post Office Building, and the colonial Palacio de la Real Audiencia de Santiago. Then make your way to the Parque Forestal, a gorgeous urban park that is home to two of Chile’s greatest art museums, before making the climb up San Cristobal Hill to gain an inspiring panorama of the city below and the ocean beyond. You’ll also tour two of Santiago’s quaintest neighborhoods, the artsy and endearing barrio of Bellavista and the handicraft village of Los Graneros del Alba.

What's Included:

Transfer
Tour
Accommodation
Day 2 - 3

Santiago – Exploring Sensational Santiago

Day 4

Puerto Varas – The Wonders of Chile

Day 5

Bariloche – Crossing into Argentina

Day 6

Bariloche – The Many Charms of Beautiful Bariloche

Day 7

Buenos Aires – Discovering the Paris of Latin America

Day 8 - 9

Buenos Aires – The Mystique and Romance of Argentine Cowboys

Day 10

Colonia del Sacramento – A Luxurious Getaway on the Shores of the Rio de la Plata

Day 11 - 12

Montevideo – Encountering Uruguay

Day 13 - 14

Montevideo – An Introduction to Magnificent Montevideo

Day 15 - 16

Iguazu Falls – Turning to a Natural Wonder

Day 17

Buenos Aires – The Glories of Nature, the Grandeur of Civilization

Day 18

Buenos Aires – Returning Home

Trip Highlights

  • Explore the best cities and most picturesque countryside of Chile, from spellbinding Santiago to miraculous Valparaiso, to the valleys that produce some of South America’s best wine
  • Journey into Chile’s Lakes Region, soaking in the natural beauty and the charm of its people, before crossing into Argentina in inimitable fashion
  • Spend some time in Bariloche, the center of Argentina’s wine industry and a true paradise for food lovers and outdoor lovers alike
  • Visit brilliant Buenos Aires, one of the most fascinating cities on the planet, where the past comes alive and the present glimmers with the passion of the Paris of Latin America
  • Make a brief stop in underrated and overlooked Uruguay, where you’ll find yourself knee deep in history in Colonia del Sacramento and up to your ears in culture in Montevideo
  • Experience the unsurpassed splendor of Iguazu Falls, as hundreds of cataracts create an atmosphere that puts the falls at Niagara to shame

Detailed Description

South American lovers, rejoice: this comprehensive tour of one of Earth’s great destinations is sure to leave you pulsing with joy and filled with stories that you’ll be telling for the rest of your life. On this 17-day South America itinerary, you’ll be treated to all the highlights of Chile, Argentina, and Uruguay, from the best hotels to the finest wines, to the natural marvels that will leave you speechless, breathless and yearning for more. And with some of the friendliest and most fascinating locals leading you every step of the way, you’re sure to fall in love with this unmatched region.

See the capitals of three mighty and magnificent nations, from the surf of the Pacific crashing off the shores near Santiago, to the pulsing beat of tango music in the streets of Buenos Aires, to the monuments, and to the glorious past in Montevideo. Enjoy the best that Mother Nature has to offer, from the azure lakes and verdant valleys of Chile, to the graceful power of Iguazu Falls. Enjoy fresh seafood and perfectly prepared grass-fed beef, the sumptuous boldness of a Bariloche Malbec and the piquant bite of a Pisco sour. If you’ve ever dreamed of the splendor of Valparaiso and the luxury of Buenos Aires; if you’ve ever yearned for the power of the Andes and the magic of Colonia; if you’ve ever desired a trip that is unlike anything you’ve ever experienced before, then wait no longer, because South America is waiting for you.

Starting Price

$8,100 per person (excluding international flights)

Your Zicasso trip is fully customizable, and this sample itinerary is a starting place for your travel plans. Actual costs are dynamic, and your selection of accommodations and activities, your season of travel, and other such variables will bring this budget guideline up or down. Throughout your planning experience with your Zicasso specialist, your itinerary is designed around your budget. You can book your trip when you are satisfied with every detail. Planning your trip with a Zicasso travel specialist is a free service.

What's Included

  • Accommodations
  • In-country transportation
  • Some or all activities and tours
  • Expert trip planning
  • 24x7 support during your trip

Your final trip cost will vary based on your selected accommodations, activities, meals, and other trip elements that you opt to include.

4.9

Verified Traveler Reviews

Based on 1035 reviews

Argentina, Chile Tour Review: Perito Moreno, Los Glaciares, Atacama, Torres del Paine, Buenos Aires, Hiking, Cooking Class, 25 Days

My trip was an incredible adventure, which I feel fortunate to have experienced. The excursions were well chosen and hotels outstanding. The logistics of a long trip with over six destinations and activities in the desert, mountains, and urban areas were artfully arranged by Zicasso’s travel specialist and supported by vendors and transit agencies. I had a support network that allowed me to totally enjoy the beautiful and diverse environments, cultures, and activities.

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Argentina Tour Review: Buenos Aires, Iguazu, Bariloche, El Calafate, El Chalten, 2 Weeks

We take great pleasure in saying our Patagonian adventure through Zicasso and the tour operator was near perfect. Our sincere thanks to our travel specialist and everyone at the tour operator for the red-carpet treatment we received at every destination on our itinerary: namely Buenos Aires, Iguazú, Bariloche, El Calafate, and El Chalten. We commend everyone involved in the personalized communication, planning and execution of our two exciting weeks traveling throughout Argentina.

Beginning in December 2025, the travel specialist and his team worked out every detail of travel in Argentina's fall season: all our domestic flights, customized tours, airport transfers, and, most importantly, the most knowledgeable, engaging guides we could ever have imagined. We can't make enough positive comments about our first Patagonian adventure.

Every driver arrived promptly, putting us immediately at ease. Every evening, team members messaged us on WhatsApp to remind us of the next day's transfers and tours. They followed up immediately with answers to any questions we had.

All of our guides were exceptional. Their passion and depth of knowledge made our tours more fascinating and entertaining than any we've ever experienced. We could not have planned anything remotely close to the guides the tour operator included for each tour.

We will most assuredly utilize the services of the travel specialist at the best tour company we have ever found for adventures in South America.

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Chile, Argentina Trip Review: San Rafael Lagoon, Torres del Paine, Perito Moreno Glacier, Iguazu Falls, Glacier Walk, 19 Days

We had great hotels, great guides, great experiences, and great support via WhatsApp from Zicasso's travel specialists during the trip.

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Brazil Vacation Review: Iguazu Falls, Fortaleza, Beaches, 10 Nights

We had a great travel experience with Zicasso's travel company. Brazil is a wonderful country to visit. The people we encountered were very courteous, helpful, and happy.

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Chile Travel Review: Santiago, Patagonia, Hiking, 1 Week

It was a very well-organized trip with a lot of attention to detail. The tour guides were professional and kind. I fell sick the first day in Santiago and the hotel staff were extremely helpful with organizing a doctor and helping me get appropriate medication in the middle of the night. Patagonia is a truly wonderful place and the arrangements were excellent. Thank you.

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Argentina, Chile Tour Review: Torres del Paine, 5 Nights

Zicasso’s travel specialist was very easy to work with and put together the unique itinerary that we were looking for. He was also very attentive to our needs during the trip. I would definitely recommend him and his company to anyone traveling to southern South America.

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Customizable Itinerary

This is a sample itinerary to inspire a personalized trip designed with your travel specialist.

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